Canadian Journal of Applied Sciences
EVALUATION OF ANTIEMETIC POTENTIAL OF AQUEOUS BARK EXTRACT OF CINNAMON LOUREIROI

Authors: Imran Ahmad Khan

Keywords: Antiemetic, Cinnamons loureiroi, chi-ck emesis model, Domperidone, Metoclopramide, Chlorpromazine

Abstract

Crude aqueous bark extract of Cinnamon loureiroi. was evaluated for anti-emetic potential. Emesis was induced by the oral administration of copper sulphate and fresh aqueous extract of Brassica compestris to male chicks of fifteen days age. The anti-emetic activity was determined by calculating the mean decrease in number of retching in contrast with those of control. Cinnamon (3 and 6 mg / kg body weight orally) showed anti-emetic activity when compared with standard drugs Chlorpromazine , Domperidone and Metoclopramide. Both the extracts, showed the antiemetic activity, highest (79.22% inhibition) and the lowest (58. 94 % inhibition) in copper sulphate induced emesis and highest (81.91% ) and the lowest( 59.57%) in Brassica compestris induced emesis.

Article Type:Original research article
Received: 2014-01-10
Accepted: 2014-01-25
First Published:5/3/2024 7:09:11 AM
First Page & Last Page: 26 - 32
Collection Year:2014