Journal of Applied Pharmacy
THE EFFECT AND COMPLICATION INDUCED BY ANTIHISTAMINE DRUGS IN THE LOCAL POPULATION; A CROSS SECTIONAL STUDY

Authors: Alveena Sadiq*1,2,SamanShahab Farooqui1, Atiya Kaleem1, QuratulainPirzada1,3, Saima iqbal1,Khadija Aslam1 and Safila Naveed1

Keywords:

Awareness, Allergy, Antihistamine, Sedations, Cetirizine, Loratadine.

Abstract

Background

As we know that allergies all over the world is the utmost medical problem and in Karachi, Pakistan, every 2nd person is complaining of allergy due to pollution. Antihistamines are considered as one the most widely used and abused medications after analgesics. Antihistamines are generally used in the palliative treatment in   allergic condition like hay fever urticaria. Some of pruritus, rhinitis, conjunctivitis, nasal discharge, mild asthma etc. 

Methodology

The study conducts among the population of Karachi to check awareness regarding antihistamine and its complication i.e. sedation affect daily routine or not. This may help to estimate the level of awareness among the population of Karachi towards the usage of these drugs and accordingly enable us to make efforts to improve the same.   

Result

Total no of participants is 470 that responded to the survey, and the finding indicated that the main antihistamine used is cetirizine and loratadine. A proportion of 91.5% of total number of respondent have used antihistamine for allergic disease and have information about antihistamine medications and 8.5% had  used antihistamine for allergic diseases while 53.2% used antihistamine as a OTC drug and 45.8% used as a prescription drug.31.9% have experienced sedation after using antihistamine while 44.7% have not  experienced any sedative effect. Nearly 23.4% not aware of the sedative effect of antihistamine. 

CONCLUSION

The most used antihistamine is cetirizine and loratadine and the most participants have information regarding the complications and the side effects of antihistamine in general.

Article Type:Original research article
Received: 2021-07-25
Accepted: 2021-10-07
First Published:5/16/2024 9:42:25 PM
First Page & Last Page: 27 - 35
Collection Year:2021