Journal of Applied Pharmacy
FREE RADICAL SCAVENGING ACTIVITY OF SIX MEDICINAL PLANTS OF BANGLADESH: A POTENTIAL SOURCE OF NATURAL ANTIOXIDANT

Authors: Shakhawat Hossain1 , Jahidul Islam1 , Firoj Ahmed2 , Md. Amjad Hossain3 , Mohammad Abdul Kaium Siddiki3 and S. M. Moazzem Hossen4

Keywords: Ipomoea paniculata; withania somnifera; mikania cordata; abroma augusta; bombax ceiba; oxalis corniculata; antioxidant; DPPH free-radical.

Abstract

The crude meoh extracts of six medicinal plants of bangladesh (ipomoea paniculata, withania somnifera, mikania cordata, abroma augusta, bombax ceiba, and oxalis corniculata) were screened for primary types of phytochemicals presence and in-vitro anti-oxidant activity by using the 1,1-diphenyl-2-picryldydrazyl-hydrate (dpph) free radical scavenging assay. Of all of them, the meoh extracts of the leaves of withania somnifera and oxalis corniculata showed strong antioxidant activity (ic50:27.8 and 19.98 ?g/ml), while the meoh extracts of ipomoea paniculata, abroma augusta and bombax ceiba showed moderate activity (ic50: 86.48, 101.4 and 58.6 ?g/ml, respectively). Moreover, mild anti-oxidant activity was observed with the meoh extract of mikania cordata (ic50 > 300 ?g/ml).

Article Type:Original research article
Received: 2015-01-05
Accepted: 2015-01-20
First Published:7/14/2024 11:02:50 PM
First Page & Last Page: 78 - 84
Collection Year:2015