SERUM THYROID AND ITS REGULATORY HORMONE LEVELS IN OBESE WOMEN WITH SEDENTARY LIFESTYLE
Authors: Tasnim Farasat1 , Tahira Mughal2 , Sidra Farooq1
Keywords: Thyroid hormone, Obese women, Sedentary lifestyle
Abstract
The aim of this study was to investigate the thyroid hormones (T3, T4) and its
regulatory hormone (TSH) levels in obese women with sedentary life style.
The studied population consists of 180 female subjects of age group 20-45
years. The subjects were divided into three categories on the basis of body
mass index: normal weight subjects (n= 60) overweight subjects (n=60) and
obese subjects (n=60). Thyroid hormone levels were assessed by commercially
available Enzyme linked immunosorbent assay (ELISA) kits. It was observed
that thyroid functionswere normal in range in all subjects but when comparison
was done between the groups using one way ANOVA, the serum T3
concentration was significantly low in obese and overweight subjects in
comparison with normal weight subjects (p = 0.005). Serum T4 concentration
was significantly lowers in overweight and obese subjects in comparison to
normal weight (p = 0.005). Serum TSH concentration was significantly higher
in obese in comparison with normal weight (p = 0.005) while it was not
significantly higher in overweight subjects (p = 0.05).
Article Type:Original research article
Received: 2010-11-05
Accepted: 2010-12-05
First Published:7/14/2024 5:30:19 AM
First Page & Last Page: 370 - 375